White Peony P.E

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WHITE PEONY extract

Botanical name: Paeollia lactiflora Pallas

Part of plant used: Roots

Active ingredients: Paeoniflorin, Albiflorin

Specification: Paeoniflorin 90%, 40%, 20%

Assay method: HPLC

Peony root or white peony has been used traditionally as medicine in China for at least 1,500 years. Its main use is as a women’s tonic herb for heavy and/or painful periods and menopausal problems. In addition, peony root is used as an analgesic, anti-inflammatory and antispasmodic drug in the treatment of dysmenorrhoea, amenorrhoea, and pain in the abdomen and chest .

References:

Ohta Hiroyuki, et al. Peony and its major constituent , paeoniflorin, improved radial maze performance impaired by scopolamine in rats. Pharmacol., Biochem. Behav. 1993, 45(3), 719-723.

Takeda, Shuichi; et al. Absorption and excretion of paeoniflorin in rats. J. Pharm. Pharmacol. 1995, 47(12A)1036-1040.

Hsu FL, Lai CW, Cheng JT. Antihyperglycemic effects of paeoniflorin and 8-debenzoylpaeoniflorin, glucosides from the root of Paeonia lactiflora. Planta Med 1997, 63(4): 323-325

He JX, Akao T, Tani T. Influence of co-administered antibiotics on the pharmacokinetic fate in rats of paeoniflorin and its active metabolite paeonimetabolin-I from Shaoyao-Gancao-tang. J Pharm Pharmacol. 2003, 55(3): 313-321.

Murakami, Nobutoshi. New bioactive monoterpene glycosides from Paeoniae Radix. Chem. Pharm. Bull. 1996. 44(6), 1279-1281.

Shimizu, Mineo; et al. Antiinflammatory topical preparations containing Paeonia triterpenoids. JP 08 59, 472 (1996)

Sugaya, Aiko. Inhibitory effect of peony root extract on pentylentetrazole-induced, intracellular calcium increase. Bioimages 1993, 1 (2), 115-123

Tomoda M, Matsumoto K, Shimizu N, Gonda R, Ohara N. Characterization of a neutral and an acidic polysaccharide having immunological activities from the root of Paeonia lactiflora. Biol Pharm Bull 1993, 16(12): 1207-1210

Tomoda M, Matsumoto K, Shimizu N, Gonda R, Ohara N, Hirabayashi K. An acidic polysaccharide with immunological activities from the root of Paeonia lactiflora. Biol Pharm Bull 1994, 17(9):1161-1164

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